Top 5 CBD Products for Cholesterol 2024

Managing healthy cholesterol levels is key to overall wellbeing, but medication side effects can deter long-term adherence. Early research indicates CBD may offer a natural way to maintain cholesterol equilibrium through its interaction with metabolic pathways.

In preclinical studies, CBD demonstrates an ability to reduce fat accumulation and weight gain, implying potential to positively influence lipid profiles.

CBD also appears to upregulate enzymes related to cholesterol metabolism and downregulate specific factors causing liver inflammation from high cholesterol.

While current data is preliminary, CBD’s emerging cholesterol-lowering mechanisms make it an intriguing supplemental or alternative therapy.

In this article, we highlight highly bioavailable CBD oils, capsules, and gummies to potentially incorporate into your cholesterol wellness regimen after consulting your doctor.

Read on to learn how hemp-derived CBD could help restore balance to your lipid profile through anti-inflammatory action and more.

Our Process for Selecting the Best CBD for Cholesterol

Choosing the perfect CBD product isn’t easy, given the sheer number of options available today. But don’t fret – we’re here to help. We’ve meticulously examined each product with a stringent set of criteria to ensure quality, safety, and transparency.

Unwavering Quality Standards

Each CBD product that made our list meets these essentials:

  1. It’s made with hemp cultivated right here in the U.S., adhering to high agricultural standards.
  2. It contains no more than 0.3% THC, as verified by its certificate of analysis (COA) – ensuring you don’t get any unwanted psychoactive effects.
  3. It’s cleared tests for pesticides, heavy metals, and molds, in line with the COA, safeguarding you from harmful contaminants.
  4. It’s undergone third-party testing by an ISO 17025-compliant lab, assuring an unbiased quality check.

Delving Deeper into the Details

But we didn’t stop at these basics. We delved further to shortlist products with the following factors in mind:

  1. The potency of each product, because when it comes to CBD, the dosage makes a difference.
  2. The ingredient list: we favored products with ingredients specifically known for stress relief.
  3. The company’s certifications and manufacturing processes to ensure the product comes from trusted, responsible sources.
  4. The reputation of each brand, including customer reviews, giving us a glimpse into real-life user experiences.
  5. A keen eye for red flags, like unsupported health claims about their products or a history of FDA warning letters.

Through this thorough and methodical approach, we’re confident that the products we’ve selected are of the highest quality.

Why Only Five Products in Our Guide?

In the landscape of CBD, options abound. You might stumble upon guides featuring 15, 20, or even more products. But let’s face it, isn’t that a bit excessive?

We understand that the wide array of choices can be overwhelming. And after analyzing dozens of merchants and hundreds of products on the market, we’ve found that high-quality CBD products are, in essence, pretty similar. Their differences often boil down to nuances in taste, nothing more.

So, we took a different approach. We wanted to curate a concise list that won’t drown you in a sea of seemingly endless choices.

So we’ve handpicked only five products. But make no mistake, these are not just any five products. They’re the cream of the crop, the top dogs, the… well, you get the point.

Every product on this list is of the highest quality and offers the best price-per-milligram ratio.

So you can be confident that you’re not just getting the best CBD – you’re also getting the best value for your money. Because we believe that when it comes to your health and wellness journey, less can truly be more.

Best 5 CBD Products Effective for Cholesterol

CBD Gummies for Sleep

CBD Gummies for Sleep
CBD Gummies for Sleep

At the price of $50, cbdMD’s Full Spectrum CBD Gummies for Sleep offers a unique blend for better sleep. Combining CBD with THC and natural sleep aids like melatonin, lemon balm, ashwagandha, chamomile, and more, these gummies aim to provide restful sleep. While the product offers 50 mg CBD and 2 mg THC per serving, it also includes 5 mg of Melatonin to support healthy sleep cycles.

The gummies are vegan and gluten-free, flavored with natural raspberry. According to the company, these gummies may help support natural melatonin production and promote calming effects. However, the consumer must take note of the warning about chemicals like myrcene and THC, as mentioned by the State of California.

CBD Capsules

CBD Capsules
CBD Capsules

Priced at $110, cbdMD’s full spectrum CBD capsules aim to make hemp benefits easily accessible. With 200 mg CBD and 2 mg THC per serving, the capsules include other cannabinoids like CBN, CBG, CBC, and select terpenes. These capsules may offer calming, rejuvenating effects throughout the day and night.

Derived from non-GMO hemp grown in the U.S., the capsules are vegan and gluten-free. According to the company’s instructions, consumers should take two capsules daily with water or other non-alcoholic beverages. The high concentration of hemp-derived cannabinoids may give it a more natural, bitter taste.

Full Spectrum Calming CBD Gummies

Full Spectrum Calming CBD Gummies
Full Spectrum Calming CBD Gummies

For $110, cbdMD’s Calming Full Spectrum CBD Gummies offers relaxation with 200 mg CBD and 4 mg THC per serving. Including ingredients like ashwagandha, lemon balm, chamomile, and more, these gummies aim to provide natural calming benefits.

Vegan and gluten-free with natural mixed berry flavors, these gummies are designed to help individuals unwind from stress. According to the company, the product’s THC content is not enough to cause intoxication for most people, but the relaxation effect may vary based on individual physiology.

Delta-9 THC Oil Drops CBN CBD Sweet Dreams Blend

Delta-9 THC Oil Drops CBN CBD Sweet Dreams Blend
Delta-9 THC Oil Drops CBN CBD Sweet Dreams Blend

Priced at $85, this product is a blend of full spectrum CBD, 2.25 mg of THC, 10 mg of CBN, and MCT oil, aiming to enhance sleep and relaxation. The blend also includes proprietary sleep terpenes, with organic, non-GMO, and vegan ingredients.

According to the product details, the combination of these elements may result in a calming effect, deeper sleep, and no “hangover” feeling upon waking. However, consumers should be aware of the potential psychotropic effect mentioned in the product warning.

CBD Broad Spectrum Oil Tincture

CBD Broad Spectrum Oil Tincture
CBD Broad Spectrum Oil Tincture

Available for $60, CBD Broad Spectrum Oil Tincture by cbdMD offers a simple and pure way to consume CBD. This THC-free formula infused in MCT oil comes in different concentrations, aiming to provide versatile CBD intake.

Derived from U.S. hemp and third-party lab-tested, the tincture is vegan and gluten-free. With a quick absorption rate and potential use in recipes and drinks, this product offers a user-friendly way to include CBD into one’s routine. Be mindful of the potential bitter taste in higher concentrations of hemp-derived cannabinoids.

What the Research Says About CBD and Cholesterol

Useful Drugs for the Treatment of Obesity? Special Focus on Cannabidiol

The article, published in March 2020, explores the potential use of phytocannabinoids, with a special focus on Cannabidiol (CBD), in the treatment of obesity. It delves into the mechanisms by which CBD may influence various metabolic processes, including lipid metabolism and mitochondrial activity.

CBD’s role in reducing fat accumulation and weight gain has been highlighted in the article. It was found that CBD treatment induced mitochondrial activation and increased oxygen consumption, possibly explaining reduced fat accumulation. Additionally, CBD inhibited weight gain in rats subjected to a high-fat diet, likely mediated by the CB2 receptor. However, the article emphasizes that more research is needed to uncover the exact mechanisms by which CBD induces these metabolic changes.

While the article does not specifically discuss the use of CBD for lowering cholesterol, the findings related to CBD’s impact on lipid metabolism and weight reduction may imply potential benefits in managing cholesterol levels. The study’s insights into CBD’s anti-obesity properties and its effects on lipid metabolism could be relevant to understanding how CBD might be used in cholesterol management.

Cannabidiol protects livers against nonalcoholic steatohepatitis

The research focuses on the effects of Cannabidiol (CBD), a nonpsychoactive constituent of marijuana, on liver inflammation induced by a high-fat high cholesterol diet. The study explores how CBD can alleviate liver inflammation by inhibiting specific pathways in both in vivo and in vitro studies. The researchers found that CBD significantly reduced the activation of certain proteins and pathways that lead to inflammation in the liver.

The outcomes of this research provide valuable insights into the potential use of CBD for lowering cholesterol. By inhibiting the activation of specific pathways related to inflammation, CBD demonstrated a protective effect against liver conditions induced by high cholesterol diets. This suppression of inflammation-related factors in the liver suggests that CBD might be a promising therapeutic agent for managing cholesterol levels and related liver issues. The study’s findings contribute to the growing body of evidence supporting the medicinal benefits of CBD, particularly in the context of liver health and cholesterol management.

The non-psychoactive plant cannabinoid, cannabidiol affects cholesterol metabolism-related genes in microglial cells

The article, published in 2011, explores the effects of Cannabidiol (CBD) on cholesterol metabolism-related genes in microglial cells. The researchers investigated how CBD, a non-psychoactive plant cannabinoid, modulates lipid-related genes in these cells. The study found that CBD significantly upregulated the mRNAs of enzymes related to cholesterol metabolism, such as sterol-O-acyl transferase (Soat2) and sterol 27-hydroxylase (Cyp27a1). Additionally, CBD increased the mRNA of the lipid droplet-associated protein, perilipin2 (Plin2). The study also revealed that pretreatment with a cholesterol chelating agent reversed the CBD-induced increase in Soat2 mRNA but not in Plin2 mRNA.

The outcomes of this research provide insights into the potential use of CBD for lowering cholesterol. By upregulating specific enzymes and proteins related to cholesterol metabolism, CBD may modulate cholesterol homeostasis in microglial cells. This modulation could have implications for the treatment of cholesterol-related conditions, although further research would be needed to fully understand the mechanisms and potential applications in human health.

Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes

The article, published online on August 29, 2016, investigates the effects of Cannabidiol (CBD) and D9-tetrahydrocannabivarin (THCV) on patients with type 2 diabetes. The study lasted 13 weeks and included 62 subjects.

The research aimed to understand how CBD and THCV affect lipid and glucose metabolism. THCV significantly decreased fasting plasma glucose and improved pancreatic b-cell function, while CBD had effects on resistin and glucose-dependent insulinotropic peptide.

While the study did not show a significant impact on HDL-cholesterol, the effects on glucose metabolism suggest potential benefits for cholesterol management. The findings open new possibilities for further research and therapeutic applications in reducing cholesterol.

How to Shop for CBD for Cholesterol


Oil – CBD oils and tinctures allow rapid absorption into the bloodstream to potentially influence lipid metabolism quickly. Oils also enable precise microdosing to calibrate effects.


Full spectrum CBD provides the full range of plant compounds to maximize therapeutic effects through the entourage effect. The combination of cannabinoids and terpenes enhances efficacy.


Higher strength CBD oils around 1000-1500mg offer more powerful benefits by engaging more endocannabinoid receptors. However, it’s ideal to start low at 300mg and gradually increase under medical supervision.

In summary, a full spectrum CBD oil or tincture at a relatively high 1000-1500mg potency will provide maximum therapeutic effects. Lower regular doses can help maintain cholesterol balance. Consult a doctor before using any CBD.


How much CBD oil to lower cholesterol?

The appropriate CBD oil dosage for cholesterol reduction varies based on factors like body weight, metabolism, and cholesterol levels. It’s best to consult a healthcare professional for personalized guidance and to ensure safe and effective use.

What does CBD oil do for cholesterol?

While research shows promising potential, CBD’s exact effects on cholesterol are still being studied. Some studies suggest that CBD may have anti-inflammatory properties that could support heart health and potentially impact cholesterol levels positively. However, more research is needed to establish definitive conclusions.

How does CBD oil tincture affect cholesterol medications?

CBD can interact with certain cholesterol medications, affecting their absorption or metabolism. It’s crucial to inform your healthcare provider about your CBD usage to avoid potential interactions or dosage adjustments.

How effective is CBD oil in reducing cholesterol without medication?

CBD’s effectiveness in reducing cholesterol levels without medication may vary among individuals. While it shows promise as a natural remedy, it should not replace prescribed cholesterol-lowering medications without medical supervision.

How much does CBD lower my cholesterol, and how long does it take?

CBD’s impact on cholesterol varies based on multiple factors, such as dosage, frequency of use, and an individual’s unique response to the compound. The time frame for noticeable effects can differ among users and may require consistent use over weeks or months.

How does CBD oil affect cholesterol?

CBD may positively affect cholesterol levels due to its potential anti-inflammatory properties and interaction with the body’s endocannabinoid system. However, more research is essential to understand the exact mechanisms involved.

How long does it take for CBD to lower cholesterol?

The time it takes for CBD to lower cholesterol is not universally consistent. Individual responses, dosage, lifestyle factors, and overall health play a role in determining the timeline for potential improvements.

How much CBD to lower cholesterol?

Determining the ideal CBD dosage for cholesterol management depends on various factors, including individual health conditions and desired outcomes. It is crucial to work with a healthcare professional to establish the most suitable dosage.

How long does it take for CBD to lower cholesterol?

The time frame for CBD’s impact on cholesterol levels can vary significantly. Some individuals may experience positive changes within weeks, while others may require more extended periods of consistent use.

How much CBD oil do you need for cholesterol and diabetes?

The appropriate CBD oil dosage for managing cholesterol and diabetes should be determined in consultation with a healthcare provider, taking into account the specific needs and medical history of the individual.

Scientists uncover how CBD treats MS, alters cholesterol metabolism

Exciting research indicates that CBD may have potential therapeutic effects on multiple sclerosis (MS) and may also impact cholesterol metabolism favorably. However, extensive studies are necessary to fully comprehend the mechanisms and clinical implications.