Top CBD for Crohn’s Relief in 2024

If you or a loved one are struggling with Crohn’s disease, you’re likely aware of the chronic inflammation and pain that comes with this disorder. But have you considered the potential relief that CBD may provide? According to recent scientific research, there’s growing interest in using cannabis, specifically CBD, to alleviate symptoms of Crohn’s disease.

Various studies have explored the potential anti-inflammatory effects of cannabinoids like THC and CBD, showing mixed results.

Some trials, such as the combination of CBD and THC, achieved remission in 65% of the cannabis group, improving quality of life and Crohn’s disease activity index (CDAI) scores. Others found CBD to be safe but not necessarily effective, possibly due to small doses or lack of synergism with other cannabinoids.

In this article, we’ll dive into the research and help you explore the best CBD products for Crohn’s disease.

While the studies reveal a complex relationship and further research is needed to fully understand the benefits and risks, our guide aims to bring clarity to this emerging area of treatment. Join us as we explore this promising frontier in the battle against Crohn’s disease.

Our Process for Selecting the Best CBD for Crohn’s Disease

Choosing the perfect CBD product isn’t easy, given the sheer number of options available today. But don’t fret – we’re here to help. We’ve meticulously examined each product with a stringent set of criteria to ensure quality, safety, and transparency.

Unwavering Quality Standards

Each CBD product that made our list meets these essentials:

  1. It’s made with hemp cultivated right here in the U.S., adhering to high agricultural standards.
  2. It contains no more than 0.3% THC, as verified by its certificate of analysis (COA) – ensuring you don’t get any unwanted psychoactive effects.
  3. It’s cleared tests for pesticides, heavy metals, and molds, in line with the COA, safeguarding you from harmful contaminants.
  4. It’s undergone third-party testing by an ISO 17025-compliant lab, assuring an unbiased quality check.

Delving Deeper into the Details

But we didn’t stop at these basics. We delved further to shortlist products with the following factors in mind:

  1. The potency of each product, because when it comes to CBD, the dosage makes a difference.
  2. The ingredient list: we favored products with ingredients specifically known for stress relief.
  3. The company’s certifications and manufacturing processes to ensure the product comes from trusted, responsible sources.
  4. The reputation of each brand, including customer reviews, giving us a glimpse into real-life user experiences.
  5. A keen eye for red flags, like unsupported health claims about their products or a history of FDA warning letters.

Through this thorough and methodical approach, we’re confident that the products we’ve selected are of the highest quality.

Why Only Five Products in Our Guide?

In the landscape of CBD, options abound. You might stumble upon guides featuring 15, 20, or even more products. But let’s face it, isn’t that a bit excessive?

We understand that the wide array of choices can be overwhelming. And after analyzing dozens of merchants and hundreds of products on the market, we’ve found that high-quality CBD products are, in essence, pretty similar. Their differences often boil down to nuances in taste, nothing more.

So, we took a different approach. We wanted to curate a concise list that won’t drown you in a sea of seemingly endless choices.

So we’ve handpicked only five products. But make no mistake, these are not just any five products. They’re the cream of the crop, the top dogs, the… well, you get the point.

Every product on this list is of the highest quality and offers the best price-per-milligram ratio.

So you can be confident that you’re not just getting the best CBD – you’re also getting the best value for your money. Because we believe that when it comes to your health and wellness journey, less can truly be more.

Best 5 CBD Products Effective for Crohn’s Disease

Delta-9 THC Gummies CBD Lemon Dream Indica

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Delta-9 THC Gummies CBD Lemon Dream Indica

These Delta-9 THC Gummies, infused with CBD and melatonin, are derived from organic hemp. With 25mg CBD and 5mg THC per serving, they may offer anti-inflammatory properties. THC’s interaction with the endocannabinoid system can possibly help reduce inflammation, a symptom often associated with Crohn’s disease. However, THC may cause psychotropic effects, so caution is advised.

CBD Full Spectrum Oil Softgels

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CBD Full Spectrum Oil Softgels

Full spectrum CBD Oil Softgels are formulated with CBD and THC to balance relief and support. Full spectrum CBD is known for its anti-inflammatory properties, which could assist in alleviating inflammation-related symptoms in Crohn’s disease. With up to 6000 mg CBD, these softgels may offer a convenient way to incorporate CBD into daily routines.

CBD Focus Capsules

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CBD Focus Capsules

Designed for focus and mental clarity, CBD Focus Capsules are formulated with CBD, CBG, and other ingredients. Though primarily aimed at improving focus, CBD’s potential anti-inflammatory effects may provide support for those experiencing inflammation due to Crohn’s disease. It is advisable to consult with a healthcare professional for specific applications related to Crohn’s disease.


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Loaded with 10MG of premium broad-spectrum CBD, BINOID GUMMIES are THC-free and made in the USA. Broad-spectrum CBD has been studied for its anti-inflammatory properties, which could be beneficial for inflammation-related conditions like Crohn’s disease. These gummies offer a tasty way to consume CBD, but specific applications to Crohn’s disease should be discussed with a healthcare provider.

CBD CBN Oil Calming Tincture

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CBD CBN Oil Calming Tincture

Full Spectrum CBD with CBN, this calming tincture is designed to aid sleep without leaving you groggy. In addition to sleep support, full spectrum CBD’s known anti-inflammatory properties could assist with inflammation control, a common issue in Crohn’s disease. CBN, a derivative of THC, may further contribute to potential therapeutic benefits. Consultation with healthcare professionals for Crohn’s disease applications is recommended.

What the Research Says About CBD and Crohn’s Disease

An overview of cannabis based treatment in Crohn’s disease

The article, published in 2020, provides an overview of cannabis-based treatment in Crohn’s disease. Crohn’s disease is a chronic inflammatory bowel condition, and there has been interest in using cannabis to alleviate symptoms. The article highlights the role of the endocannabinoid system in regulating gastrointestinal functions and explores the potential anti-inflammatory effects of cannabinoids like THC and CBD.

The article reviews three randomized controlled trials involving 93 participants with Crohn’s disease. The first trial showed a reduction in Crohn’s disease activity index (CDAI) with THC, but the results were not conclusive. The second trial, using CBD, did not show significant effects, possibly due to the small dose used. The third trial, using a combination of CBD and THC, achieved remission in 65% of the cannabis group, showing improvement in quality of life and CDAI scores.

In conclusion, the article emphasizes that cannabis seems to have therapeutic potential in Crohn’s disease, but more research is needed to fully understand the effects of various cannabis compounds.

Oral CBD-rich Cannabis Induces Clinical but Not Endoscopic Response in Patients with Crohn’s Disease, a Randomised Controlled Trial

The article was published in 2021 and focuses on a randomized controlled trial that investigated the effects of oral CBD-rich cannabis on patients with Crohn’s Disease (CD). The study was conducted with 56 patients, who were given either cannabis oil containing CBD/THC or a placebo for 8 weeks. The main goal was to assess the effect of cannabidiol (CBD)-rich cannabis oil for inducing remission in CD.

The outcomes of the study revealed that the CBD-rich cannabis treatment led to significant clinical improvement in the quality of life for the patients without causing significant changes in inflammatory parameters or endoscopic scores. The median quality of life score improved in the cannabis group compared to the placebo group after 8 weeks.

Cannabis for the Treatment of Crohn’s Disease and Ulcerative Colitis: Evidence From Cochrane Reviews

The article, published in April 2020, systematically reviewed the safety and effectiveness of cannabis and cannabinoids treatment for Crohn’s disease (CD) and ulcerative colitis (UC). The researchers conducted a comprehensive search of various databases and included five randomized controlled trials in their analysis, encompassing 185 participants.

The studies examined different forms of cannabis and cannabinoids, including cannabis cigarettes, cannabis oil, and cannabidiol, and compared them to placebo groups. The results were mixed and varied across the studies. One CD study showed 45% of the cannabis cigarette group experienced clinical remission compared to 10% in the placebo group. Another CD study did not show significant rates of clinical remission. A UC study also did not have significant clinical remission rates. Adverse events were more prevalent in the cannabis groups for both CD and UC studies.

Cannabis for the treatment of Crohn’s disease

The article, published in 2018, explores the potential use of cannabis and cannabinoids for the treatment of Crohn’s disease, a chronic condition that causes inflammation in the gastrointestinal tract. The researchers conducted a systematic review of three studies involving 93 participants, assessing the efficacy and safety of cannabis in various forms, including cigarettes containing THC and cannabis oil with different concentrations of cannabinoids.

The findings of the article are inconclusive regarding the definitive benefits of cannabis for Crohn’s disease. One study showed improvement in symptoms with cannabis cigarettes but also reported mild side effects like sleepiness, nausea, and confusion. Another study comparing cannabis oil to placebo found no significant difference in clinical remission rates. The third study observed differences in quality of life and Crohn’s disease activity index (CDAI) scores with cannabis oil treatment but did not report on clinical remission or response.

In summary, the article suggests that the effects of cannabis and cannabis oil on Crohn’s disease are uncertain, and no firm conclusions can be drawn regarding their efficacy and safety. The authors emphasize the need for further research with larger participant numbers and different doses and delivery methods of cannabis to fully understand its potential benefits and risks in treating Crohn’s disease.

Low-Dose Cannabidiol Is Safe but Not Effective in the Treatment for Crohn’s Disease

The article, published in 2017, presents the findings of a randomized controlled trial that investigated the effects of low-dose Cannabidiol (CBD) on Crohn’s disease. The study involved 20 patients aged between 18 and 75 years who were not responding to standard treatments. They were randomized to receive either 10 mg of oral CBD or a placebo twice daily for 8 weeks. The study aimed to assess the anti-inflammatory effects of CBD on Crohn’s disease, a chronic inflammatory disorder of the gastrointestinal tract.

The results of the study showed that CBD was safe but did not have beneficial effects on Crohn’s disease. The average Crohn’s Disease Activity Index (CDAI) before and after CBD consumption remained statistically similar in both the CBD and placebo groups. Hemoglobin, albumin, and kidney and liver function tests also remained unchanged, and no side effects were observed. The study concluded that CBD was safe but not effective in treating Crohn’s disease. The lack of effect could be due to the small dose of CBD, the small number of patients in the study, or the absence of synergism with other cannabinoids.

Inflammatory Bowel Disease and Cannabis

The article, published in 2021, provides a practical approach for clinicians regarding the relationship between Inflammatory Bowel Disease (IBD) and cannabis. It explores the nuanced relationship between cannabis and the treatment of IBD by summarizing current research and discussing practical considerations surrounding its use.

Cannabis has gained popularity for the treatment of chronic conditions like IBD, but its exact role remains uncertain. While it may help with symptom management, such as alleviating abdominal pain, joint pain, cramping, and diarrhea, it has not been proven to help with inflammation or to fundamentally correct underlying disease processes. The article also highlights concerns like dosing inconsistencies, dependence, and cannabinoid hyperemesis syndrome.

Through population studies, cannabis has been shown to alleviate symptoms associated with IBD. However, clinical studies have found mixed results. Some studies suggest benefits in symptom management and quality of life, but others have found no significant reduction in inflammation or improvement in endoscopic healing. The role of cannabis in the treatment of IBD is complex and may be decided on a case-by-case basis, taking into account the unique attributes of each individual patient.

Cannabis and Canabidinoids on the Inflammatory Bowel Diseases

The article, published on 22 April 2020, explores the effects of Cannabis sativa (CS) on Inflammatory Bowel Diseases (IBD), specifically ulcerative colitis (UC) and Crohn’s disease (CD).

The main compounds of CS, tetrahydrocannabinol (THC) and cannabidiol (CBD), are known for their anti-inflammatory and antioxidant properties. The article investigates the potential therapeutic benefits of CS for UC and CD, considering the improvement in disease scores and quality of life.

However, the authors also emphasize the need for caution, as there is no standardization in the studies regarding the variety and part of the plant used, route of administration, and doses.

They conclude that while CS shows relevant antioxidant and anti-inflammatory effects that could improve UC and CD, it is not yet possible to establish a treatment criterion.

Therefore, they suggest caution in using CS in the therapeutic approach of IBD until more standardized clinical trials are performed.

How to Shop for CBD for Crohn’s Disease


Oil – CBD oils and tinctures that are taken under the tongue may work best for Crohn’s disease as they allow rapid absorption into the bloodstream. This provides faster relief for symptoms like abdominal pain and diarrhea. Oils also make it easy to precisely adjust doses.


Full Spectrum – Full spectrum CBD retains all the natural compounds in the hemp plant, including a small amount of THC. This creates an “entourage effect” for enhanced anti-inflammatory and pain-relieving benefits that may better manage Crohn’s symptoms.


Higher potency CBD oils around 1000mg may be optimal for Crohn’s disease, which can cause severe inflammation and pain. However, it’s important to start low at 300mg and gradually increase the dosage to find the most effective amount tailored to your needs.

In summary, look for a full spectrum CBD oil or tincture at a high potency for maximum relief potential. Start low and go slow in finding your ideal dose. Consult a doctor before using CBD for Crohn’s disease.


How does CBD help with Crohn’s disease?

Studies show CBD may reduce inflammation, pain, and diarrhea in Crohn’s disease by interacting with the endocannabinoid system. CBD may also help relieve anxiety and depression symptoms associated with Crohn’s. More research is still needed.

What’s the best way to take CBD for Crohn’s?

Sublingual CBD oils and tinctures allow fast absorption into the bloodstream. CBD capsules and edibles provide longer relief. Topicals can also help when applied directly to the abdomen. Vaping works fast but may irritate lungs.

What dosage of CBD should I try for Crohn’s?

There are no official guidelines yet. In studies dosages ranged from 5-50 mg per kg of body weight daily. It’s ideal to start low at 10-20 mg and increase slowly every few days to find the most effective dose for you.

How long does it take for CBD to work for Crohn’s?

Relief from symptoms like abdominal pain and diarrhea may begin within 15-30 minutes of taking CBD sublingually. However, the full effects likely take several weeks of consistent dosing to build up in your system. Give it at least 1 month.

Does CBD cure or treat Crohn’s disease?

No, CBD is not a cure for Crohn’s disease. However, it may effectively help manage various digestive and psychological symptoms. CBD should complement traditional Crohn’s medications and lifestyle changes recommended by your gastroenterologist.

Are there drug interactions with CBD and Crohn’s meds?

Yes. CBD can potentially interact with medications used for Crohn’s like steroids, immunosuppressants, and biologics. Discuss using CBD with your doctor and pharmacist to check for interactions and monitor side effects.

Is CBD safe long-term for Crohn’s disease?

Early research did not identify serious safety concerns with long-term CBD use. However, studies on long-term use are very limited. It’s a good idea to take breaks from CBD and get regular checkups if using it chronically.

Can CBD worsen Crohn’s disease?

In rare cases, CBD could potentially exacerbate symptoms like diarrhea according to some doctors. Those with Crohn’s may want to use lower doses of CBD and monitor for any increase in digestive issues. Discuss using CBD for Crohn’s with your GI doctor.

Will health insurance cover CBD for Crohn’s disease?

Most insurance plans will not cover CBD products yet since they are not FDA-approved medications. Some plans may cover Epidiolex, the only approved CBD drug. Check with your insurance provider about CBD coverage options.

Can you build a tolerance to CBD for Crohn’s relief?

Yes, it is possible to build up a tolerance over time, requiring higher doses for the same effects. Avoid this by taking occasional CBD breaks and varying usage methods. Make dosage changes only under medical supervision.