Best CBD for Nausea 2024: Top 5 Picks

Nausea is more than just a discomfort; for patients undergoing treatments like chemotherapy, it can be a continuous struggle. But what if we told you there’s hope on the horizon?

Research like the study on “Cannabinoid Regulation of Acute and Anticipatory Nausea” and others provide compelling evidence of how cannabidiol (CBD) might be the answer.

These studies explore the use of cannabinoids, including CBD, in treating the troublesome symptoms of nausea.

For instance, the research demonstrates that CBD can suppress vomiting through indirect activation of specific receptors in the brain, and even the combination of THC and CBD has shown promising results in reducing chemotherapy-induced vomiting and nausea.

It’s like unlocking a door that’s been closed for so long, and we’re here to take you on this enlightening journey. In this article, we’ll delve into the best CBD products specifically tailored for nausea.

So if you or a loved one has been battling this unsettling sensation, stay tuned as we explore the potential relief that could be just a few clicks away!

Our Process for Selecting the Best CBD for Nausea

Choosing the perfect CBD product isn’t easy, given the sheer number of options available today. But don’t fret – we’re here to help. We’ve meticulously examined each product with a stringent set of criteria to ensure quality, safety, and transparency.

Unwavering Quality Standards

Each CBD product that made our list meets these essentials:

  1. It’s made with hemp cultivated right here in the U.S., adhering to high agricultural standards.
  2. It contains no more than 0.3% THC, as verified by its certificate of analysis (COA) – ensuring you don’t get any unwanted psychoactive effects.
  3. It’s cleared tests for pesticides, heavy metals, and molds, in line with the COA, safeguarding you from harmful contaminants.
  4. It’s undergone third-party testing by an ISO 17025-compliant lab, assuring an unbiased quality check.

Delving Deeper into the Details

But we didn’t stop at these basics. We delved further to shortlist products with the following factors in mind:

  1. The potency of each product, because when it comes to CBD, the dosage makes a difference.
  2. The ingredient list: we favored products with ingredients specifically known for stress relief.
  3. The company’s certifications and manufacturing processes to ensure the product comes from trusted, responsible sources.
  4. The reputation of each brand, including customer reviews, giving us a glimpse into real-life user experiences.
  5. A keen eye for red flags, like unsupported health claims about their products or a history of FDA warning letters.

Through this thorough and methodical approach, we’re confident that the products we’ve selected are of the highest quality.

Why Only Five Products in Our Guide?

In the landscape of CBD, options abound. You might stumble upon guides featuring 15, 20, or even more products. But let’s face it, isn’t that a bit excessive?

We understand that the wide array of choices can be overwhelming. And after analyzing dozens of merchants and hundreds of products on the market, we’ve found that high-quality CBD products are, in essence, pretty similar. Their differences often boil down to nuances in taste, nothing more.

So, we took a different approach. We wanted to curate a concise list that won’t drown you in a sea of seemingly endless choices.

So we’ve handpicked only five products. But make no mistake, these are not just any five products. They’re the cream of the crop, the top dogs, the… well, you get the point.

Every product on this list is of the highest quality and offers the best price-per-milligram ratio.

So you can be confident that you’re not just getting the best CBD – you’re also getting the best value for your money. Because we believe that when it comes to your health and wellness journey, less can truly be more.

Best 5 CBD Products Effective for Nausea

CBD Gummies with Turmeric and Spirulina

CBD Gummies with Turmeric and Spirulina
CBD Gummies with Turmeric and Spirulina

These CBD Gummies are combined with turmeric and spirulina for a unique supplement designed to enhance focus and energy. With 50mg of broad spectrum CBD and 50mg of phosphatidylserine, these gummies are organic, vegan, and non-GMO. The calmness induced by CBD may help in nausea management, by relaxing the digestive tract and reducing anxiety, often a trigger for nausea.

Turmeric, a powerful anti-inflammatory, and spirulina, rich in nutrients, may provide additional support for general wellness. While these gummies are primarily aimed at focus and energy, the ingredients have been known to offer some relief from nausea, although more research may be needed.

CBD Sleep Aid Gummies

CBD Sleep Aid Gummies
CBD Sleep Aid Gummies

Designed to aid sleep, these CBD Sleep Aid Gummies combine CBD with melatonin, L-theanine, and calming herbs. With 5 mg of melatonin per serving, they are vegan-friendly and gluten-free. The calming effects of CBD can reduce stress, a common factor in nausea, and possibly provide relief.

Herbs like Chamomile are often used as a natural remedy for gastrointestinal disturbances including nausea. By combining these natural ingredients with CBD, these gummies may promote relaxation and a good night’s sleep, and indirectly aid in managing nausea symptoms.

1500mg Full Spectrum CBD Oil

1500mg Full Spectrum CBD Oil
1500mg Full Spectrum CBD Oil

This Full Spectrum CBD oil contains 50mg of CBD with minor traces of THC. Extracted from Organically Grown Colorado Hemp and blended with organic MCT Oil, it offers a wide range of cannabinoids, terpenes, and flavonoids. While primarily designed for other health benefits, Full Spectrum CBD can have calming effects on the digestive system, possibly easing nausea symptoms.

THC, although present in small quantities, may add to these effects. Studies have shown THC to be effective in reducing nausea and vomiting in medical treatments, making this oil potentially useful for those dealing with nausea.

Delta-9 THC Gummies CBD Lemon Dream Indica

Delta-9 THC Gummies CBD Lemon Dream Indica
Delta-9 THC Gummies CBD Lemon Dream Indica

These Lemon Dream THC Gummies offer 25mg CBD and 5mg THC per serving, providing both relaxation and wellness benefits. THC has been studied for its effectiveness in reducing nausea, especially in medical contexts. Along with full spectrum CBD and natural melatonin, these gummies may aid in sleep and relaxation.

While the main goal of these gummies is deep relaxation and sleep enhancement, the blend of ingredients may also support those experiencing nausea by calming the digestive system and providing a restful state of mind.

25mg Full Spectrum CBD Softgels

25mg Full Spectrum CBD Softgels
25mg Full Spectrum CBD Softgels

Enclosed in vegan, non-GMO, and Gluten-Free softgels, these Full Spectrum CBD Softgels provide 25mg of CBD per serving. Extracted from Organically Grown Colorado Hemp, these softgels offer essential cannabinoids, terpenes, and flavonoids. As CBD is known for its calming properties, these softgels may support the reduction of nausea symptoms by calming the digestive tract.

Faster absorption and the full spectrum nature of this product make it a potential option for those seeking relief from nausea, although it’s mainly targeted towards general wellness and the enhanced effects of CBD.

What the Research Says About CBD and Nausea

Cannabinoid Regulation of Acute and Anticipatory Nausea

The study titled “Cannabinoid Regulation of Acute and Anticipatory Nausea” was published in 2016. It focuses on the distressing problem of chemotherapy-induced nausea, which remains a significant issue for patients undergoing treatment. Even with the introduction of newer antiemetics, nausea continues to be problematic, and when acute nausea is not properly managed, it can lead to anticipatory nausea, for which there are no effective treatments.

The study explores both human and pre-clinical animal literature, examining the potential for exogenous (externally administered) and endogenous (internally produced) cannabinoid treatments to regulate chemotherapy-induced nausea. The pre-clinical evidence highlights the need to evaluate the antinausea potential of cannabidiol (CBD), cannabidiolic acid, and treatments that boost the functioning of the endocannabinoid system in human clinical trials.

The detailed results of the study show that Delta-9-tetrahydrocannabinol (THC), the major psychoactive component of cannabis, has been effective in reducing chemotherapy-induced vomiting and nausea when smoked or orally administered. Synthetic THC, such as dronabinol and nabilone, has also been shown to be effective in reducing these symptoms. The study also mentions the potential of a cannabis-based medicine called Sativex, containing both THC and CBD, to reduce delayed nausea.

Furthermore, the study emphasizes the unique ability of cannabinoids to manage nausea, a symptom that current antiemetic treatments cannot control. The findings also suggest that endogenous cannabinoids may be important neuromodulators involved in the experience of nausea, with decreased levels evident with nausea-inducing manipulations.

Overall, the study underscores the therapeutic potential of cannabinoids to reduce chemotherapy-induced nausea and highlights the need for further research and clinical trials to explore alternative therapeutics for anticipatory nausea, as current medicines are insufficient. It’s like discovering a new way to help people feel better during a tough time, using something that has been around for thousands of years but is only now being understood in this context.

Regulation of nausea and vomiting by cannabinoids

The study titled “Regulation of nausea and vomiting by cannabinoids” was published in the British Journal of Pharmacology in 2011. The research was conducted by Linda A. Parker, Erin M. Rock, and Cheryl L. Limebeer from the Department of Psychology and Collaborative Neuroscience Program at the University of Guelph, Ontario, Canada.

The study focuses on how manipulating the endocannabinoid system can regulate nausea and vomiting in humans and other animals. The researchers found that cannabinoids, including cannabidiol (CBD), have an anti-emetic effect across various animals capable of vomiting in response to toxic challenges. The study also highlights the potential of cannabinoids in treating symptoms of nausea and anticipatory nausea in chemotherapy patients, which are often less controlled by conventional pharmaceutical agents.

The research provides evidence that cannabinoids may suppress vomiting through both central and peripheral mechanisms. For example, CB1 agonism suppresses vomiting, and this effect is reversed by CB1 antagonism. The primary non-psychoactive compound in cannabis, CBD, also suppresses nausea and vomiting within a limited dose range. The anti-nausea effects of CBD may be mediated by indirect activation of specific receptors in the brain.

The study also explores the anti-emetic effects of cannabinoids in human clinical trials. It compares the effectiveness of synthetic cannabinoids like D9-THC and nabilone with other anti-emetic drugs. The results indicate that cannabinoids are at least as effective as dopamine antagonists in suppressing nausea and vomiting produced by chemotherapy. Some evidence also suggests that cannabinoids may be effective in treating more difficult to control symptoms of nausea and delayed nausea and vomiting in children.

In animal models, cannabinoids have been shown to reduce vomiting in various species, including cats, pigeons, ferrets, and shrews. The study explores the mechanisms of action, suggesting that cannabinoids may act mainly via peripheral CB1 receptors to decrease intestinal motility but may act centrally to attenuate emesis.

In conclusion, the study provides substantial evidence that cannabinoids, including CBD, may be clinically effective for treating both nausea and vomiting produced by chemotherapy or other therapeutic treatments. It opens up new avenues for understanding the role of the endocannabinoid system in regulating these symptoms and offers promising insights into potential therapeutic applications of cannabinoids in medicine.

Oral THC:CBD cannabis extract for refractory chemotherapy-induced nausea and vomiting: a randomised, placebo-controlled, phase II crossover trial

The study in question was a significant multicenter experiment, and although the document doesn’t specify the year, it aimed to evaluate whether a combination of THC and CBD (two components found in cannabis) could prevent nausea and vomiting caused by chemotherapy. The results presented are from the second phase of the study, which was conducted across two parts, known as phase II and III.

In the experiment, 81 people participated, and they were given either the THC:CBD capsules or placebo pills. They took these capsules three times daily from the day before chemotherapy to the fifth day after. The main goal was to see how many participants had a complete response, meaning no vomiting or nausea. Among the 81 participants, 72 finished both cycles of the study, and their results were used in the final analysis.

The structure of the study included one cycle of 1-4 THC:CBD capsules (each with 2.5 mg of THC and 2.5 mg of CBD) and one cycle of placebo. With 80 participants, the study had enough statistical power to detect a 20% improvement in symptoms of nausea and vomiting.

The results of the study were encouraging. The THC:CBD treatment improved complete response rates from 14% to 25%. Additionally, participants using THC:CBD experienced less vomiting, needed fewer extra medications, and had less significant nausea. However, 31% of the participants experienced side effects like sleepiness, dizziness, or confusion. Still, 83% of participants preferred the cannabis treatment over the placebo, and no serious side effects were linked to the THC:CBD treatment.

In conclusion, the addition of THC:CBD to standard treatments for chemotherapy patients seemed to reduce nausea and vomiting but did come with some additional side effects. Most participants preferred this treatment to a placebo, and the researchers found the results promising enough to continue to the next phase of the study.

How to Shop for CBD for Nausea

Here’s a friendly guide to help you pick the right CBD product for your nausea, based on form, types, and potency.

Form: Finding Your Perfect Match

Oil: The Quick Solution

If speed is your priority, CBD oil might be the perfect pick. Acting in just a few minutes and lasting 2-3 hours, it’s efficient and easy to dose. And guess what? It’s also excellent for microdosing, subtly enhancing focus, productivity, or mood.

Gummies: The Tasty Long-Term Relief

Favoring flavor? CBD gummies offer a tasty experience that lasts 4-6 hours. They’re easy to dose and portable, with options like sugar-free, vegan, or gluten-free. And if you’re in a hurry, fast-acting gummies kick in about 10 minutes.

Capsules: Convenient and Mess-Free

Love convenience? CBD capsules take 30-60 minutes to work but come in a pre-measured, mess-free format. Just like a regular pill, they provide all the benefits of CBD oil in a capsule.

Types: What’s In It For You?

Isolate: The Purest Form

If THC isn’t your thing, CBD isolate offers a cheaper, THC-free option. However, you’ll miss out on the potential benefits of the full plant extract.

Full-Spectrum: The Whole Package

For a full experience, full-spectrum CBD oil includes all of the cannabinoids. It won’t get you high but offers the potential ‘entourage effect,’ maximizing medicinal properties.

Broad-Spectrum: Best of Both Worlds

Like a middle ground? Broad-spectrum CBD oil gives you the benefits of the entourage effect without THC. And no worries about drug tests detecting THC here.

Potency: Finding Your Strength

Low-Potency (300 mg): For General Wellness

New to CBD? Low-potency might be your best bet, boosting general health and helping to lower stress levels.

Mid-Potency (600 mg): For Moderate Needs

Dealing with moderate stress or discomfort? Mid-potency could be your ideal choice.

High-Potency (1,000 mg): For Serious Concerns

Facing sleep issues or chronic pain? High-potency CBD oil offers potent solutions for these ailments.


Here are 10 common questions and answers about using CBD for nausea:

How does CBD help with nausea?

Studies show CBD may help reduce nausea by interacting with serotonin receptors involved in vomiting. CBD may also reduce inflammation and block nausea signals to the brain. However, more research is still needed.

What’s the best way to take CBD oil for nausea?

Sublingual CBD oils and tinctures tend to work fast for nausea relief as they enter the bloodstream quickly. CBD capsules and edibles are longer-lasting options. Topicals may help when nausea is triggered by inflammation. Vaping works fast but may irritate the stomach.

What dose of CBD should I try for nausea?

There are no official dosage guidelines yet. In studies, doses of 5-40 mg daily were used for nausea and vomiting. It’s ideal to start with 2-5 mg and increase slowly as needed. Work with a doctor to find the most effective dose for your nausea.

When should I take CBD for nausea – with food or on an empty stomach?

Taking CBD oil with food may help minimize potential stomach upset as a side effect. However, taking it on an empty stomach allows for faster absorption and relief. Monitor what works best for your symptoms.

How fast does CBD relieve nausea?

Most people feel some relief from nausea within 15-30 minutes of ingesting CBD oil sublingually or vaping. However, finding your optimal dosage and delivery method may require some trial and error. Full effects likely take 1-2 weeks of consistent use.

Can CBD make nausea worse?

In rare cases, CBD may cause diarrhea, stomach pain, or appetite changes that exacerbate nausea temporarily. Starting with small doses and taking it with food can help minimize this risk. Discontinue use if nausea persists or worsens.

Does CBD help with chemotherapy nausea?

A few studies show CBD and THC may reduce chemotherapy-induced nausea and vomiting. However, more clinical trials are still needed. CBD should complement, not replace, medications prescribed for chemo nausea. Discuss with your oncologist first.

Can you take too much CBD for nausea?

Yes, high doses of CBD may trigger nausea and diarrhea as side effects. It’s important to take only the amount needed for symptom relief. Start low and go slow when finding your optimal dosage. Never exceed 200 mg in a dose without medical guidance.

Is CBD safe to use while pregnant for nausea?

No, CBD should be avoided during pregnancy as the risks to the developing fetus are unknown. Discuss safer anti-nausea medication options with your OB-GYN. Do not start taking CBD if you are pregnant without your doctor’s approval.

Are there drug interactions with CBD and nausea meds?

CBD can interact with certain prescription anti-nausea medications, especially those metabolized through the liver’s cytochrome P450 system. Discuss using CBD with your doctor and monitor side effects closely if combining it with nausea medications.