Best CBD for Parkinson 2024: Top 5 Picks

Parkinson’s disease (PD) is a complex and often debilitating condition, leaving many in search of relief. Science is beginning to shed light on a promising ally in the fight against Parkinson’s – cannabidiol, or CBD.

Recent studies, such as those published on PubMed and NCBI, have shown CBD’s potential as a neuroprotective and neuromodulatory agent.

Researchers are focusing on its effects on the basal ganglia circuit, and the potential of CBD in activating receptors that influence movement, inflammation, and oxidative stress.

While evidence is emerging, and larger trials are still needed to conclusively support the use of CBD for PD, the initial findings are indeed promising. Are you intrigued?

Well, stay with us as we delve into the 5 best CBD products that might offer a new glimmer of hope for those grappling with Parkinson’s disease.

It’s not just about relief; it’s about rediscovering quality of life.

Our Process for Selecting the Best CBD for Parkinson’s Disease

Choosing the perfect CBD product isn’t easy, given the sheer number of options available today. But don’t fret – we’re here to help. We’ve meticulously examined each product with a stringent set of criteria to ensure quality, safety, and transparency.

Unwavering Quality Standards

Each CBD product that made our list meets these essentials:

  1. It’s made with hemp cultivated right here in the U.S., adhering to high agricultural standards.
  2. It contains no more than 0.3% THC, as verified by its certificate of analysis (COA) – ensuring you don’t get any unwanted psychoactive effects.
  3. It’s cleared tests for pesticides, heavy metals, and molds, in line with the COA, safeguarding you from harmful contaminants.
  4. It’s undergone third-party testing by an ISO 17025-compliant lab, assuring an unbiased quality check.

Delving Deeper into the Details

But we didn’t stop at these basics. We delved further to shortlist products with the following factors in mind:

  1. The potency of each product, because when it comes to CBD, the dosage makes a difference.
  2. The ingredient list: we favored products with ingredients specifically known for stress relief.
  3. The company’s certifications and manufacturing processes to ensure the product comes from trusted, responsible sources.
  4. The reputation of each brand, including customer reviews, giving us a glimpse into real-life user experiences.
  5. A keen eye for red flags, like unsupported health claims about their products or a history of FDA warning letters.

Through this thorough and methodical approach, we’re confident that the products we’ve selected are of the highest quality.

Why Only Five Products in Our Guide?

In the landscape of CBD, options abound. You might stumble upon guides featuring 15, 20, or even more products. But let’s face it, isn’t that a bit excessive?

We understand that the wide array of choices can be overwhelming. And after analyzing dozens of merchants and hundreds of products on the market, we’ve found that high-quality CBD products are, in essence, pretty similar. Their differences often boil down to nuances in taste, nothing more.

So, we took a different approach. We wanted to curate a concise list that won’t drown you in a sea of seemingly endless choices.

So we’ve handpicked only five products. But make no mistake, these are not just any five products. They’re the cream of the crop, the top dogs, the… well, you get the point.

Every product on this list is of the highest quality and offers the best price-per-milligram ratio.

So you can be confident that you’re not just getting the best CBD – you’re also getting the best value for your money. Because we believe that when it comes to your health and wellness journey, less can truly be more.

Best 5 CBD Products Effective for Parkinson’s Disease

PM Softgel Capsules

PM Softgel Capsules

The PM Softgel Capsules from cbdMD could help Parkinson’s patients sleep better and manage symptoms. Each softgel contains broad spectrum CBD, CBN, melatonin, and calming herbs like valerian root. CBN has relaxing, sleep-promoting effects that may ease common Parkinson’s sleep disruptions like insomnia and REM sleep behavior disorder. Melatonin helps restore healthy sleep cycles. Better sleep allows the brain to recover and reduces PD fatigue. With regular use, these capsules may significantly improve sleep quality for those with Parkinson’s.

CBD Calm Capsules

CBD Calm Capsules

The CBD Calm Capsules from cbdMD are formulated to promote relaxation, which could benefit those with Parkinson’s disease. The capsules contain broad spectrum CBD plus stress-relieving ingredients like L-theanine, lemon balm, and rhodiola. CBD interacts with endocannabinoid receptors to reduce anxiety and improve mood. The additional herbal extracts enhance these calming effects. By lowering stress and anxiety, the capsules may help PD patients better manage and cope with their symptoms.

CBD Gummies for Sleep with Melatonin

CBD Gummies for Sleep with Melatonin

These CBD gummies from CBDfx combine broad spectrum CBD with melatonin to promote better sleep, which could benefit Parkinson’s patients. Melatonin helps regulate circadian rhythms, while CBD provides calming effects to reduce sleep disruptions. Together, they may improve insomnia and REM sleep behavior disorder common in PD. The gummies also contain chamomile, passionflower, and lemon balm to further relax the nervous system. Getting consistent, restorative sleep allows the brain to heal and manage PD symptoms better.

CBD Full Spectrum Oil Tincture

CBD Full Spectrum Oil Tincture

This full spectrum CBD oil from cbdMD may help relieve Parkinson’s symptoms thanks to the entourage effect from numerous cannabinoids. The THC content is minimal, but the array of cannabinoids and terpenes work synergistically to reduce inflammation, protect neurons, and ease motor deficits associated with PD. The oil can be taken sublingually for fast absorption and quick relief of tremors, stiffness, and pain. Start with a low dose and increase gradually to find the optimal amount.



The Good Night CBD Oil from Binoid combines broad spectrum CBD with CBN and sleep-promoting herbs. CBN has demonstrated sedative effects that can improve sleep issues associated with Parkinson’s. Valerian root and lemon balm also quiet the nervous system. Better sleep allows the brain to heal and manage PD symptoms more effectively. Taken nightly, this CBD oil may help those with Parkinson’s achieve deeper, more restorative sleep.

What the Research Says About CBD and Parkinson’s Disease

Cannabidiol as a Therapeutic Target: Evidence of its Neuroprotective and Neuromodulatory Function in Parkinson’s Disease

The article was published on 15th December 2020. It explores the potential of cannabidiol (CBD), a non-psychotropic phytocannabinoid, as a therapeutic target for Parkinson’s disease (PD). The research delves into the neuroprotective and neuromodulatory functions of CBD, focusing on its effects on the basal ganglia circuit, which regulates movement. The study highlights the role of CBD in compensating for the endocannabinoid system (ECS) and its potential as a neuroprotector in various PD models. The article also discusses the activation of different receptors by CBD, opening new avenues for understanding its effects at the neural communication level.

The outcomes of the research provide valuable insights into the use of CBD for treating Parkinson’s disease. The study demonstrates that CBD has compensatory effects on the ECS, acting as a neuromodulator and neuroprotector. It emphasizes the potential of CBD to activate various receptors, including CB1, CB2, and TRPV-1, which are expressed in the dopaminergic neurons of the nigro-striatal pathway. These findings suggest that CBD’s ability to influence these receptors could be a viable treatment alternative for both Parkinson’s disease and the long-term dyskinesias induced by levodopa treatment, a common medication for PD. The research opens new possibilities for understanding CBD’s role in improving neuronal communication, making it a promising therapeutic avenue for Parkinson’s disease.

Cannabidiol in Parkinson’s disease

The article, published in 2020, explores the potential of cannabidiol (CBD) in treating Parkinson’s disease (PD). It highlights a few small studies that have shown CBD might reduce psychotic symptoms and improve sleep-related behaviors in PD patients.

However, the article emphasizes that these studies are not enough to conclusively support the use of CBD for PD. The evidence is still insufficient, and larger trials are needed to truly understand CBD’s effectiveness in treating PD.

Effects of cannabidiol (CBD) in neuropsychiatric disorders: A review of pre-clinical and clinical findings

The article, published in 2019, provides a comprehensive review of the effects of cannabidiol (CBD) in various neuropsychiatric disorders. It summarizes selected pre-clinical and clinical studies, highlighting CBD’s potential therapeutic properties, including anti-epileptic, anti-oxidant, anti-inflammatory, anti-psychotic, anxiolytic, and anti-depressant effects. The article also discusses the pharmacology of CBD, its complex pharmacodynamics, and its interaction with various molecular targets.

Regarding Parkinson’s disease (PD), the article mentions that patients with PD have reported improvements in sleep and better quality of life with CBD. However, it emphasizes that larger scale, randomized, placebo-controlled studies are still needed to fully understand the therapeutic potential of CBD on the symptoms of PD-associated movement disorders. The article does not delve into specific mechanisms related to PD but provides a general overview of CBD’s effects in neuropsychiatric disorders, including its potential benefits for PD.

Cannabidiol for neurodegenerative disorders: A comprehensive review

The article, published on 25th October 2022, explores the potential of cannabidiol (CBD) in treating neurodegenerative disorders, including Parkinson’s disease (PD). The authors emphasize CBD’s antioxidant and anti-inflammatory properties, which are considered vital in its neuroprotective behavior.

In relation to Parkinson’s disease, the article highlights CBD’s ability to inhibit specific enzymes and activate certain receptors, which may play a role in preventing harmful processes in PD.

The review concludes that CBD’s multifaceted actions make it a promising therapeutic agent for Parkinson’s disease, focusing on its effects on inflammation and oxidative stress.

How to Shop for CBD for Parkinson’s Disease

When shopping for CBD to manage Parkinson’s symptoms, a fast-acting oil or gummy is ideal for quick relief when tremors, muscle rigidity, or other symptoms flare up.


CBD oil can be taken sublingually for the fastest absorption and effects, usually within minutes. This allows for easy dosing whenever symptoms worsen. The oil also lasts 2-3 hours, providing sustained relief. Oils give the most precision for dosing.

CBD Gummies

Though they take 30-45 minutes to start working, CBD gummies offer portable and precise dosing. Their pre-measured doses make it easy to maintain consistent CBD levels. Choose fast-acting gummies for more immediate relief. Gummies mask the earthy CBD taste.

CBD Capsules

While not as fast-acting as oils or gummies, capsules offer convenient daily CBD dosing without the taste. Their slower release may help maintain stable CBD levels for ongoing control of Parkinson’s symptoms.

Finding the Right Type of CBD

For Parkinson’s, a broad or full-spectrum CBD product maximizes therapeutic benefit.

Broad-Spectrum CBD

Broad-spectrum CBD contains beneficial terpenes and cannabinoids but not THC. This provides entourage benefits without psychoactivity or legal concerns. The additional compounds enhance CBD’s effects.

Full-Spectrum CBD

Full-spectrum CBD also offers entourage benefits, but does contain a small amount of THC. While not enough to be impairing, full-spectrum CBD may cause failed drug tests. Check local laws before using products with THC.

Choosing an Effective Potency

Higher potency CBD around 600-1000mg maximizes Parkinson’s symptom relief.

  • Low potency (300mg) – Best for very mild symptoms
  • Medium potency (600mg) – Better for moderate Parkinson’s symptoms
  • High potency (1000mg) – Ideal for severe tremors, stiffness, and pain

Start low and increase dosage gradually as needed to find the most effective amount for your needs. Discuss optimal potency with your doctor.


How can CBD oil be used to manage Parkinson’s symptoms?

CBD oil may help relieve symptoms like tremors, stiffness, and pain. It can be taken orally twice a day, using an eyedropper under the tongue for fast absorption. CBD oil can also be mixed into foods or beverages. Start with a low dose like 15-30mg and increase slowly as needed. The effects are felt within 30 minutes and last for several hours.

What evidence is there that CBD can help Parkinson’s disease?

Studies show CBD may protect dopamine-producing neurons, reducing damage associated with Parkinson’s. CBD also eases inflammation and oxidative stress in the brain. By interacting with endocannabinoid receptors, CBD can improve motor deficits and slow disease progression in Parkinson’s patients. More research is still needed.

Which CBD oil is considered best for Parkinson’s disease?

Full-spectrum CBD oils may be optimal for Parkinson’s symptoms because of the entourage effect from a range of cannabinoids. Broad-spectrum CBD without THC is also a good option. Look for organically grown hemp and products tested for purity and potency. A high potency around 1000mg maximizes benefits.

What are the main advantages of using CBD gummies for Parkinson’s?

CBD gummies make dosing easy with pre-measured amounts of CBD per gummy. They are discrete, portable, and mask the earthy taste of CBD oil. Choose fast-acting gummies to get relief more quickly when symptoms flare up. The effects last 4-6 hours. Take gummies as needed for tremor episodes or pain.

How much CBD oil should someone with Parkinson’s disease take daily?

There is no standard dose, but most Parkinson’s patients find relief with 25-100mg of CBD oil per day. It’s best to start low (15-30mg) and increase by 5-10mg until symptoms improve. Work closely with your doctor to find the right amount to manage symptoms without side effects.

What types of CBD products may help with Parkinson’s disease symptoms?

Oils, capsules, gummies, vapes, and topicals like creams may all help, depending on your needs. Oils offer versatile dosing, while creams target sore muscles and joints. Vaping gets CBD into the body quickly. Capsules and gummies provide simple dosing. Use a combination for whole-body relief.

Can CBD completely cure Parkinson’s disease?

No, there is currently no cure for Parkinson’s disease. However, a growing body of research shows CBD can reduce symptoms and slow the disease’s progression significantly. While not a cure, CBD may provide hope for better management of this condition. More human studies are still needed.

Are there side effects or risks with using CBD oil for Parkinson’s?

CBD is generally very safe and well-tolerated. Potential side effects include diarrhea, fatigue, and changes in appetite or weight. CBD may interact with certain medications, so discuss use with your doctor first. Start with a low CBD dose and increase slowly monitoring for any unwanted effects.

How does CBD compare to medications for treating Parkinson’s symptoms?

For many patients, a combination of CBD and prescription medications works best. CBD offers a more natural way to manage symptoms like tremors, stiffness, and pain with few side effects. It may allow lowering doses of medications like levodopa which can cause dyskinesia with long-term use.

Can CBD completely replace medications for Parkinson’s disease?

No, CBD should not replace doctor-prescribed Parkinson’s medications without medical supervision. However, growing evidence supports CBD as a complementary therapy to enhance quality of life and reduce reliance on drugs with harsh side effects. Work closely with your neurologist to incorporate CBD safely into an overall treatment plan.